Bicuspid aortic valve and its ascending aortopathy.
Curr Opin Pediatr
; 35(5): 538-545, 2023 10 01.
Article
in En
| MEDLINE
| ID: mdl-37497761
ABSTRACT
PURPOSE OF REVIEW To synthesize and critically assess recent clinical and research advancements in pediatric bicuspid aortic valve (BAV) and its associated aortopathy. RECENT FINDINGS:
In pediatric patients with BAV, progressive aortic dilation (i.e. bicuspid aortopathy) is commonly present and associated with increased risk for aortic aneurysm, dissection, and surgery in adulthood. Ongoing research explores the cause, incidence, and progression of bicuspid aortopathy to promote earlier diagnosis and improve preventive management. Recent findings include high familial incidence and need for improved familial screening; safety of recreational physical activity in most affected children; potential for medical management to slow aortic growth; feasibility of pediatric registries to evaluate longitudinal outcomes; and potential genetic and hemodynamic biomarkers for disease risk stratification.SUMMARY:
Pediatric bicuspid aortopathy is an important area for investigation and preventive management to improve long-term cardiovascular outcomes. Recent literature promotes familial screening, recreational exercise, medical prophylaxis, registry-based longitudinal evaluation, and continued scientific inquiry.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aortic Diseases
/
Bicuspid Aortic Valve Disease
/
Heart Valve Diseases
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Child
/
Humans
Language:
En
Journal:
Curr Opin Pediatr
Journal subject:
PEDIATRIA
Year:
2023
Document type:
Article